A Review of Overcome the Side Effect of Digestion Process on the Drugs
Abstract
This review involves the effect of digestion methods on the drugs and how to overcome the harms of digestion process by designing the suitable a polymeric drug system that has ability to hold out the harsh conditions of the acid in stomach. And it involves different type of backbone polymer to prepare new drug polymers form, this new polymer drugs included many benefits such as release the minimum amount of drug over an prolonged time by organized delivery of drug and the side effect of drugs will reduced. This process includes the modification of natural polymer such as chitosan, starch, cellulose, gelatin by carried out with a spacer, and grafted the new copolymer with amino drug such as amoxicillin (HA), and characterize it by UV Spectroscopes, (DSC) and (TGA) and physical properties was discussed. And know the ability of drug release in different pH. In this review we concluded that the best way to overcome the side effect of digestion process on the drugs by using the medicine as polymer drugs, and the best polymer used was natural polymers, the prepared polymer drug have thermal stability more than the drug alone, this indicate extra expire date with more safety of drug satiability.
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