Characterization of Ni(II) and Cd(II) Metal Complexes using Schiff Base Ligand derived from 2-Thiophenecarboxyldehyde and 2 Aminothiophenol
Abstract
Schiff base ligand derived from condensation of 2-aminothiophenol and 2‑thiophenecarboxyldehyde was synthesized and used for the preparation of Ni(II) and Cd(II) complexes. The synthesized ligand and complexes were analyzed by decomposition temperature, solubility, magnetic susceptibility, molar conductance and infrared spectra. The decomposition temperatures of the complexes are 212 and 221°C. Molar conductance values are 16.12 and 12.60 ohm-1cm2mol-1 respectively. New bands appeared in the IR spectra of the complexes in the range of 519 - 475 cm-1 and 462 - 448 cm-1 which indicate υ (M - N) and υ (M - S) vibrations respectively. Magnetic susceptibility measurement indicated that Ni (II) complex is paramagnetic whileCd(II) complex is diamagnetic. The solubility test revealed that all complexes and ligand are soluble in DMSO. The analytical data show the formation of 2:1 metal to ligand ratio for all complexes and suggested the formula [ML2].nH2O. The ligand and metal chelates have been studied for microbial activity using well diffusion method against selected bacteria and fungi. The results signify that Ni(II) and Cd(II) metal complexes inhibit more compared with Schiff base ligand against the same test organisms.
References
H. Adamu, Synthesis and characterization of N(1-morpholinobenzyl semicarbazide metal complex, Unpublished M.Sc. dissertation, Department of Pure and Industrial Chemistry, Bayero University, Kano, 2009.
Ali Mohammed Yimer, Chemical synthesis, spectral characterization and antimicrobial studies on complexes of Ni(II), Cu(II) and Zn(II) with N,N-di(o-hydroxybenzenoylmethylene) ethylenediamine, American Journal of Bioscience 2(6-1) (2014), 22-34.
H.N. Aliyu and H. Adamu, Synthesis and characterization of N-(I-Morpholinobenzyl) simicarbazide Manganese (II) and Iron (II) complexes, Bayero Journal of Pure and Applied Science 2(2) (2009), 143-148. https://doi.org/10.4314/bajopas.v2i2.63802
H.N. Aliyu and I. Ado, Studies of Mn (II) and Ni (II) complexes with Schiff base derived from 2-amino benzoic acid and salicylaldehyde, Bayero Journal of Pure and Applied Science 23 (2011), 245-249. https://doi.org/10.4314/bajopas.v3i1.58803
S. Arulmuragan, H.P. Kavitha and R.B. Venkatraman, Biological activities of Schiff base and its complexes, Rasayan Journal of Chemistry 3 (2010), 385-410.
M.A. Ashraf, K. Mahmood, Abdul Wajid, M.J. Maah and I.B. Yusoff, Synthesis, characterization and biological activity of Schiff bases, 2011 International Conference on Chemistry and Chemical Process, IPCBEE, Vol. 10, Singapore, 2011, pp. 256-264.
S. Bootwala, M. Tariq, S. Somasundaran and K. Aruna, Synthesis, spectroscopic and biological characterization of some transition metal complexes with ethyl 2-{[(2E, 3 Z)-4-hydroxypent-3-en-2-ylidene] amino}-4, 5, 6, 7-tetrahydro-1-benzothiophene-3-carboxylate, International Journal of Pharmacy and Biological Sciences 3 (2013), 345-354.
C. Clarkson, V.J. Maharaj, N.R. Crouch, O.M. Grace, P. Pillay, M.G. Matsabisa, N. Bhagwandin, P.J. Smith and P.I. Folb, In vitro antiplasmodial activity of medicinal plants native to or naturalized in South Africa, J. Ethnopharm. 92 (2004), 177-191. https://doi.org/10.1016/j.jep.2004.02.011
G. Devi, Studies on transition metal complexes of schiff bases derived from amino acids, Thesis, Department of Chemistry, University of Calicut, 2002.
M.A. Hadi, Preparation and Characterization of Some Transition Metal Complexes with Schiff base ligand, Journal of Kerbala University 7 (2009), 52-57.
J. Iqbal, M. Imran, S. Iqbal and S. Latif, Synthesis, Characterization and Biological Studies of 2-[phenylmethyl amino]benzoic acid and its complexes with Co(II), Ni(II), Cu(II) and Zn(II), Journal of Chem. Soc. Pakistan 29 (2007), 151-154.
K. Mounika, B. Anupama, J. Pragathi and C. Gyanakumari, Synthesis, characterization and biological activity of a Schiff base derived from 3-ethoxy salicylaldehyde and 2-amino benzoic acid and its transition metal complexes, Journal of Scientific Research 2(3) (2010), 513-524. https://doi.org/10.3329/jsr.v2i3.4899
S.A. Khan, A.M. Asiri, S. Kumar and K. Sharma, Green synthesis, antibacterial activity and computational study of pyrazoline and pyrimidine derivatives from 3-(3,4-dimethoxy-phenyl-1-(2,5-dimethyl-thiophen-3-yl)-propenone, European Journal of Chemistry 5 (2014), 85-90. https://doi.org/10.5155/eurjchem.5.1.85-90.789
A.A. Muhammed, M. Karamat and W. Abdul, Synthesis, Characterization and Biological Activity of Schiff bases, International Conference on Chemistry and Chemical Process IPCBEE Vol. 10, IACSIT Press, Singapore, 2011.
T. Mahmud, Synthesii and characterization of amino acid schiff base and their complexes with copper(II), University of Manchester, Chemistry, Manchester, UK, 2010.
G.G. Mohamed, M.M. Omar and A.M. Hindy, Metal complexes of Schiff bases: preparation, characterization, and biological activity, Turk. J. Chem. 30 (2006), 361-382.
B.N. Meyer, R.N. Ferrigni, J.E. Putnam, L.B. Jacobsen, D.E. Nichols and J.L. McLaughlin, Brine shrimp: a convenient general bioassay for active plant constituents, Planta Medica 45 (1982), 31-34. https://doi.org/10.1055/s-2007-971236
A. Prakash and A. Adhikari, Application of Schiff base and Their Metal Complexes-A Review, International Journal of Chem. Tech. Research 3 (2011), 1891-1896.
B.K. Panda and A. Chakravorty, Spectroscopic properties of inorganic and organometallic compounds, Journal of Organometallic Chemistry 690 (2005), 3169-3175.
M. Rahmatullah, S.M.I. Sadeak, S.C. Bachar, M.T. Hossain, A. Montaha Al-mamun, N. Jahan, M.H. Chowdhury, R. Jahan, D. Nasrin, M. Rahman and S. Rahman, Brine Shrimp toxicity study of different Bangladeshi medicinal plants, Advances in Natural and Applied Sciences 4(2) (2010), 73-163.
Rani Anita, Manoj Kumar, Rajshree Khare and Hardeep S. Tuli, Schiff bases as an antimicrobial agent: a review, Journal of Biological and Chemical Science 2(1) (2015), 62-91.
Sadia Afrin Dalia, Farhana Afsan, Md. Saddam Hossain, Md. Nuruzzaman Khan, C.M. Zakaria, Md. Kudrat-E-Zahan and Md. Mohsin Ali, A short review on chemistry of Schiff base metal complexes and their catalytic application, International Journal of Chemical Studies 6(3) (2018), 2859-2866.
S. Sani and M.A. Kurawa, Synthesis, characterization and antimicrobial studies of Mn(II) complex with N-salicyl-O-hydroxyphenyleneiminato Schiff base ligand, ChemSearch Journal 7(2) (2016).
U. Sani and S.A. Dailami, Synthesis, characterization, antimicrobial activity and antioxidant studies of Metal(II) complexes of Schiff base derived from 2-hydoxy-1 napthaldehyde and hydrazine monohydrate, ChemSearch Journal 6(2) (2015), 35-41.
Taghreed M. Musa, Synthesis, characterization and antimicrobial activity of some transition complexes with new Schiff base derived from Saccharine, International Research Journal of Pure and Applied Chemistry 11(2) (2016), 1-5. https://doi.org/10.9734/IRJPAC/2016/23188
Yusuf Yunusa, Synthesis, characterization and antimicrobial activity of some metal(II) Schiff base complexes, Unpublished M.Sc. dissertation, Department of Pure and Industrial Chemistry, Bayero University, Kano, 2017.
Zahraa Salim M. Al-Garawi, Ivan Hameed R. Tomi and Ali Hussein R. Al-Daraji, Synthesis and characterization of new amino acid-Schiff bases and studies their effects on the activity of ACP, PAB and NPA enzymes (in-vitro), Journal of Chemistry 9 (2012), Article ID 218675, 8 pp. https://doi.org/10.1155/2012/218675
This work is licensed under a Creative Commons Attribution 4.0 International License.
